Brian O'Neil is the chief investment officer of the Robert Wood Johnson Foundation, the nation’s largest philanthropy dedicated solely to health. He has served the foundation since 2003 and is responsible for the $11 billion investment portfolio. In this interview, he discusses his journey at the organization and how the investment office has evolved under his leadership; the foundation's accomplishments in the public health area since 1972; and why they are a strong supporter of SEO, a program committed to building diverse and inclusive organizations.