Region ranks high among Midwest cities, but number of investments has fallen. : Partly to mostly cloudy skies with scattered thunderstorms in the morning. High 87F. Winds W at 5 to 10 mph. Chance of rain 40%.. Whenever David Nicklaus posts new content, you'll get an email delivered to your inbox with a link. Any discussion of venture capital in St. Louis must start with the fact that the region has come a long way. Even after a couple of down years, the region attracts more funding for its early-stage companies than most Midwestern cities.