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HHMI is widely recognized as an innovative national philanthropy, the world’s foremost medical research organization, a leading light in science education, and a renowned institutional investor.

Located in the Washington, DC, metro area, HHMI is seeking an Investment Operations Analyst within our Investment Fund Services team to join HHMI’s investment office, which manages an endowment with net assets of approximately $22 billion. HHMI’s endowment comprises a diverse portfolio, including investments in domestic and international hedge funds, private equity funds, venture capital funds, real assets and direct co-investments, as well as publicly-traded domestic and foreign stocks, government securities, and other strategies spanning multiple asset classes.

As an Investment Operations Analyst within our Fund Services team, you will support the management of the Institute’s endowment.  Responsibilities include supporting investment operations in six broad areas: (1) management reporting; (2) performance and analytics; (3) transaction and cash processing; (4) account management and reconciliation; (5) accounting and valuation; and (6) business process and technology enhancements.  This role will be expected to contribute in all six broad areas and will gain exposure to all major asset classes.

Essential Duties and Responsibilities

The Investment Operations Analyst will support investment operations as follows:

  • Prepare, review, and publish timely and accurate internal and external reports

  • Coordinate and oversee the accurate closing of the endowment’s monthly accounting and performance records at its administrator, including reconciliations 

  • Assist with the design and implementation of business process improvements, technology enhancements, data initiatives, and reporting improvements

  • Coordinate directly with service providers to ensure the integrity and accuracy of entries made into the custody, accounting, performance measurement and fund transparency systems

  • Record transactions, valuation and performance information in accounting and performance systems, ensuring proper audit evidence is retained

  • Prepare and provide direction to the custodian for cash movements such as capital calls, distributions, subscriptions, redemptions, fees and transfers, and for internally managed equity, fixed income and foreign currency trades, ensuring timely and accurate settlement

  • Monitor ISDA and other OTC collateral management arrangements to mitigate risk

  • Cooperate with and assist in the conduct of internal/external audits

  • Communicate and coordinate the opening, closing, and maintenance of investment accounts

  • Maintain current and historical documentation related to the portfolio and benchmarks

  • Record investment terms and conditions as applicable

  • Review audit, SOC, and other reports of key business partners

  • Other duties as assigned


  • Bachelor’s degree required, preferably in Business, Accounting or Finance


  • At least 3-7 years of relevant industry experience and increasing responsibilities in investment management, accounting, performance and/or treasury operations for endowments, custodians, administrators and/or investment management firms

  • Knowledge of private and public investments (such as limited partnerships, hedge funds, private equity, stocks, bonds, derivatives, etc.) and financial reporting

Skills and Abilities

  • Impeccable ethics and personal integrity

  • Proven history of success and achievement

  • Excellent attention to detail and judgment with a commitment to delivering a high-quality work product in a proactive manner

  • Excellent analytical, research, and critical thinking skills

  • Strong written and verbal communication skills

  • Ability to learn independently and to apply previous experience to current responsibilities coupled with intellectual curiosity to increase skills and expertise

  • Desire and ability to work independently or collaboratively as needed to meet objectives, take initiative, manage multiple tasks simultaneously and meet deadlines in a dynamic, changing environment

  • Proficient and proven experience in MS Office applications, specifically Microsoft Excel for data reconciliation, analytics, aggregation, and presentation is required; Microsoft Access experience for data extraction and reporting is a plus

  • Experience with CRM software (e.g., Dynamo, Backstop), Bloomberg (Core Terminal and AIM Trading Platform), portfolio analytics applications (e.g., Caissa, Solovis), Eagle Investment Systems Star/Pace, BNY Mellon Nexen or similar custodian platforms and/or Burgiss Private Informant/Private I is a plus

Physical Requirements

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet).  

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis. 

Please Note

This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however.  Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.  

HHMI is an Equal Opportunity Employer


Jay Kolyer

Investor | Endowment

United States of America

Mark Barnard


Mark Sproles


United States of America

Ryan Matney

Investor | Endowment

United States of America

Investor | Foundation